WHYZE HEALTH
Empowering Patients and Accelerating Research with WHYZE Health
Together with AWS and Presidio, WHYZE Health has scaled across NHS networks in the UK and partnered with a major U.S. institution serving 40M+ patients. The result: faster trial recruitment, better outcomes evidence, and more inclusive healthcare innovation.
Problem
While these trials are essential, they don’t reflect the full spectrum of patients who will ultimately receive the treatments — especially those with multiple conditions, comorbidities, or living in underserved communities. To truly advance healthcare, we must go beyond controlled environments and embrace the realities of complex, diverse patient populations. This demands access to comprehensive, longitudinal data and the ability to generate real-world evidence — capturing how treatments perform in real clinical settings, not just ideal scenarios.
By bridging this evidence gap, we empower life sciences, healthcare systems, and patients to take the next leap: developing and delivering more effective, inclusive, and personalised treatments that reflect real-world complexity.
Solution
WHYZE Health deployed a secure, cloud-native Real-World Evidence (RWE) platform on AWS, leveraging its five-layer architecture to address the gap between controlled clinical trials and real-world patient complexity:
Patient Profile App: Enables individuals to aggregate and manage longitudinal health data — including chronic conditions, comorbidities, patient-generated data and real-world treatment histories— ensuring a holistic view of patient health.
Real-World Outcomes Engine: Harnesses AI/ML to analyse how treatments perform in diverse, non-trial populations, supporting value-based care, reimbursement decisions, and post-market surveillance.
Clinical Research Extension Layer: Integrates structured and unstructured data to inform trial design, validate patient suitability for clinical trials, and guide adaptive research models using real-world inputs.
FHIR-Based Ingestion & Interoperability Layer: Standardises fragmented healthcare data from EHRs, labs, patient-generated data, and wearables to ensure scalable, compliant integration across stakeholders.
Security & Compliance Framework: Enforces privacy by design with embedded clean rooms, federated learning capabilities, and full GDPR/HIPAA compliance to protect sensitive patient data during collaboration.
Why AWS & Presidio
Presidio: Experienced in regulated healthtech, agile delivery for startups, and a proven partner in cloud transformation.
AWS: Secure, Scalable, GDPR & HIPAA-eligible, with advanced AI/ML capabilities including:
- 50 plus AWS services
- Multiple AWS regions (EU and UK)
- Zero Trust Security
- Large Language Models
- Amazon SageMaker
- RAG Pipelines
- Proprietary Models trained with guidance of clinical data scientists
- MLOps
Impact
WHYZE Health is now fully production-ready and positioned for rapid international expansion across real-world research and decentralised care models:
Digitising and Structuring Real-World Data at Scale: Actively integrating and transforming millions of unstructured clinical records, lab results, and imaging files into interoperable, research-grade datasets.
Launching AI-Powered Real-World Research Matching: Delivering the next generation of AI- and GenAI-enabled tools to intelligently match patients and their holistic health records with relevant studies, based on real-world complexity and eligibility profiles.
Scaling Secure Patient Data Infrastructure Globally: Expanding the platform’s reach to manage longitudinal records for millions of patients across both the UK and U.S., with built-in privacy, consent, and compliance layers.
Defining the Future of Research-Enabled Digital Health: Positioned as the benchmark for digital transformation in life sciences — bridging the gap between clinical development, real-world outcomes, and equitable patient access.